A new fluorescent and colorimetric probe for Cu2+ in live cells.

نویسندگان

  • Wei-Yong Liu
  • Hai-Ying Li
  • Bao-Xiang Zhao
  • Jun-Ying Miao
چکیده

Based on a change in structure between spirocyclic (non-fluorescent) and ring-open (fluorescent) forms of rhodamine-based dyes, a new fluorescent and colorimetric Cu(2+) probe was designed and synthesized. Upon treatment with Cu(2+), the weakly fluorescent probe exhibited a strong fluorescence response with high selectivity. In addition, the turn-on fluorescent probe upon the addition of Cu(2+) was applied in live cell imaging.

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عنوان ژورنال:
  • The Analyst

دوره 137 15  شماره 

صفحات  -

تاریخ انتشار 2012